IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection

Inflammation is critical for controlling pathogens, but also responsible for symptoms of infectious diseases. IL-27 is an important regulator of inflammation and can limit development of IFNγ-producing Tbet(+) CD4(+) T (Th1) cells. IL-27 is thought to do this by stimulating IL-10 production by CD4(+...

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Detalles Bibliográficos
Autores principales: Montes de Oca, Marcela, de Labastida Rivera, Fabian, Winterford, Clay, Frame, Teija C. M., Ng, Susanna S., Amante, Fiona H., Edwards, Chelsea L., Bukali, Luzia, Wang, Yulin, Uzonna, Jude E., Kuns, Rachel D., Zhang, Ping, Kabat, Agnieszka, Klein Geltink, Ramon I., Pearce, Edward J., Hill, Geoffrey R., Engwerda, Christian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584222/
https://www.ncbi.nlm.nih.gov/pubmed/33049000
http://dx.doi.org/10.1371/journal.ppat.1008994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584222/
https://www.ncbi.nlm.nih.gov/pubmed/33049000
http://dx.doi.org/10.1371/journal.ppat.1008994

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