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YebC regulates variable surface antigen VlsE expression and is required for host immune evasion in Borrelia burgdorferi

Borrelia burgdorferi, the Lyme disease pathogen causes persistent infection by evading the host immune response. Differential expression of the surface-exposed lipoprotein VlsE that undergoes antigenic variation is a key immune evasion strategy employed by B. burgdorferi. Most studies focused on the...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Chen, Tong, Raghunandanan, Sajith, Xiang, Xuwu, Yang, Jing, Liu, Qiang, Edmondson, Diane G., Norris, Steven J., Yang, X. Frank, Lou, Yongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584230/
https://www.ncbi.nlm.nih.gov/pubmed/33048986
http://dx.doi.org/10.1371/journal.ppat.1008953