In vivo and ex vivo assessment of bladder hyper-permeability and using molecular targeted magnetic resonance imaging to detect claudin-2 in a mouse model for interstitial cystitis

OBJECTIVES: To determine if the URO-MCP-1 mouse model for bladder IC/BPS is associated with in vivo bladder hyper-permeability, as measured by contrast-enhanced MRI (CE-MRI), and assess whether molecular-targeted MRI (mt-MRI) can visualize in vivo claudin-2 expression as a result of bladder hyper-pe...

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Detalles Bibliográficos
Autores principales: Smith, Nataliya, Saunders, Debra, Lerner, Megan, Zalles, Michelle, Mamedova, Nadezda, Cheong, Daniel, Mohammadi, Ehsan, Yuan, Tian, Luo, Yi, Hurst, Robert E., Greenwood-Van Meerveld, Beverley, Towner, Rheal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584247/
https://www.ncbi.nlm.nih.gov/pubmed/33095778
http://dx.doi.org/10.1371/journal.pone.0239282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584247/
https://www.ncbi.nlm.nih.gov/pubmed/33095778
http://dx.doi.org/10.1371/journal.pone.0239282

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