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Learning gene networks underlying clinical phenotypes using SNP perturbation

Availability of genome sequence, molecular, and clinical phenotype data for large patient cohorts generated by recent technological advances provides an opportunity to dissect the genetic architecture of complex diseases at system level. However, previous analyses of such data have largely focused o...

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Detalles Bibliográficos
Autores principales: McCarter, Calvin, Howrylak, Judie, Kim, Seyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584257/
https://www.ncbi.nlm.nih.gov/pubmed/33095769
http://dx.doi.org/10.1371/journal.pcbi.1007940