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Learning gene networks underlying clinical phenotypes using SNP perturbation
Availability of genome sequence, molecular, and clinical phenotype data for large patient cohorts generated by recent technological advances provides an opportunity to dissect the genetic architecture of complex diseases at system level. However, previous analyses of such data have largely focused o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584257/ https://www.ncbi.nlm.nih.gov/pubmed/33095769 http://dx.doi.org/10.1371/journal.pcbi.1007940 |