Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint

[Image: see text] Immune checkpoint blockade is one of the most promising strategies of cancer immunotherapy. However, unlike classical targeted therapies, it is currently solely based on expensive monoclonal antibodies, which often inflict immune-related adverse events. Herein, we propose a novel s...

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Detalles Bibliográficos
Autores principales: Konieczny, Magdalena, Musielak, Bogdan, Kocik, Justyna, Skalniak, Lukasz, Sala, Dominik, Czub, Miroslawa, Magiera-Mularz, Katarzyna, Rodriguez, Ismael, Myrcha, Maja, Stec, Malgorzata, Siedlar, Maciej, Holak, Tad A., Plewka, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584369/
https://www.ncbi.nlm.nih.gov/pubmed/32936638
http://dx.doi.org/10.1021/acs.jmedchem.0c01260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584369/
https://www.ncbi.nlm.nih.gov/pubmed/32936638
http://dx.doi.org/10.1021/acs.jmedchem.0c01260

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