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NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge

There is an urgent need for a safe and protective vaccine to control the global spread of SARS-CoV-2 and prevent COVID-19. Here, we report the immunogenicity and protective efficacy of a SARS-CoV-2 subunit vaccine (NVX-CoV2373) produced from the full-length SARS-CoV-2 spike (S) glycoprotein stabiliz...

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Detalles Bibliográficos
Autores principales: Guebre-Xabier, Mimi, Patel, Nita, Tian, Jing-Hui, Zhou, Bin, Maciejewski, Sonia, Lam, Kristal, Portnoff, Alyse D., Massare, Michael J., Frieman, Matthew B., Piedra, Pedro A., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584426/
https://www.ncbi.nlm.nih.gov/pubmed/33139139
http://dx.doi.org/10.1016/j.vaccine.2020.10.064