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Neuroprotective Effect of Optogenetics Varies With Distance From Channelrhodopsin-2 Expression in an Amyloid-β-Injected Mouse Model of Alzheimer’s Disease

Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is the most common cause of dementia. Optogenetics uses a combination of genetic engineering and light to activate or inhibit specific neurons in the brain. Objective: The objective of the study was to examine the e...

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Detalles Bibliográficos
Autores principales: Cui, Xiaorui, Zhang, Feng, Zhang, Hui, Huang, Xi, Wang, Kewei, Huang, Ting, Yang, Xifei, Zou, Liangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584457/
https://www.ncbi.nlm.nih.gov/pubmed/33162881
http://dx.doi.org/10.3389/fnins.2020.583628