Survey of ex vivo drug combination effects in chronic lymphocytic leukemia reveals synergistic drug effects and genetic dependencies

Drug combinations that target critical pathways are a mainstay of cancer care. To improve current approaches to combination treatment of chronic lymphocytic leukemia (CLL) and gain insights into the underlying biology, we studied the effect of 352 drug combination pairs in multiple concentrations by...

Descripción completa

Detalles Bibliográficos
Autores principales: Lukas, Marina, Velten, Britta, Sellner, Leopold, Tomska, Katarzyna, Hüellein, Jennifer, Walther, Tatjana, Wagner, Lena, Muley, Carolin, Wu, Bian, Oleś, Małgorzata, Dietrich, Sascha, Jethwa, Alexander, Bohnenberger, Hanibal, Lu, Junyan, Huber, Wolfgang, Zenz, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584477/
https://www.ncbi.nlm.nih.gov/pubmed/32404973
http://dx.doi.org/10.1038/s41375-020-0846-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584477/
https://www.ncbi.nlm.nih.gov/pubmed/32404973
http://dx.doi.org/10.1038/s41375-020-0846-5

Ejemplares similares