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Targeting nuclear import and export in hematological malignancies

The transport of proteins across the nuclear membrane is a highly regulated process, essential for the cell function. This transport is actively mediated by members of the karyopherin family, termed importins, or exportins, depending on the direction of transport. These proteins play an active part...

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Detalles Bibliográficos
Autores principales: Nachmias, Boaz, Schimmer, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584478/
https://www.ncbi.nlm.nih.gov/pubmed/32624581
http://dx.doi.org/10.1038/s41375-020-0958-y