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Combined Expression of CD34 and FLT3-Internal Tandem Duplication Mutation Predicts Poor Response to Treatment in Acute Myeloid Leukemia

BACKGROUND: Acute myeloid leukemia (AML) is a common hematological malignancy associated with different cytogenetic and genetic abnormalities. METHODS: FLT3-internal tandem duplication (FLT3/ITD) mutation and CD34 expression levels were assessed in the bone marrow (BM) aspirates of 153 de novo AML p...

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Detalles Bibliográficos
Autores principales: Abdellateif, Mona S, Kassem, Amira B, EL-Meligui, Yomna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584508/
https://www.ncbi.nlm.nih.gov/pubmed/33116779
http://dx.doi.org/10.2147/IJGM.S276138