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Expanding the genetic spectrum of choroideremia in an Australian cohort: report of five novel CHM variants
Choroideremia is an X-linked chorioretinal dystrophy caused by mutations in the CHM gene. Several CHM gene replacement clinical trials are in advanced stages. In this study, we report the molecular confirmation of choroideremia in 14 Australian families sourced from the Australian Inherited Retinal...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584600/ https://www.ncbi.nlm.nih.gov/pubmed/33110609 http://dx.doi.org/10.1038/s41439-020-00122-w |