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PRL-2 phosphatase is required for vascular morphogenesis and angiogenic signaling

Protein tyrosine phosphatases are essential modulators of angiogenesis and have been identified as novel therapeutic targets in cancer and anti-angiogenesis. The roles of atypical Phosphatase of Regenerative Liver (PRL) phosphatases in this context remain poorly understood. Here, we investigate the...

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Detalles Bibliográficos
Autores principales: Poulet, Mathilde, Sirois, Jacinthe, Boyé, Kevin, Uetani, Noriko, Hardy, Serge, Daubon, Thomas, Dubrac, Alexandre, Tremblay, Michel L., Bikfalvi, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584612/
https://www.ncbi.nlm.nih.gov/pubmed/33097786
http://dx.doi.org/10.1038/s42003-020-01343-z