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Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae

The emergence of resistance to azithromycin complicates treatment of Neisseria gonorrhoeae, the etiologic agent of gonorrhea. Substantial azithromycin resistance remains unexplained after accounting for known resistance mutations. Bacterial genome-wide association studies (GWAS) can identify novel r...

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Detalles Bibliográficos
Autores principales: Ma, Kevin C., Mortimer, Tatum D., Duckett, Marissa A., Hicks, Allison L., Wheeler, Nicole E., Sánchez-Busó, Leonor, Grad, Yonatan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584619/
https://www.ncbi.nlm.nih.gov/pubmed/33097713
http://dx.doi.org/10.1038/s41467-020-19250-6