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CSF1R signaling is a regulator of pathogenesis in progressive MS

Microglia serve as the innate immune cells of the central nervous system (CNS) by providing continuous surveillance of the CNS microenvironment and initiating defense mechanisms to protect CNS tissue. Upon injury, microglia transition into an activated state altering their transcriptional profile, t...

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Detalles Bibliográficos
Autores principales: Hagan, Nellwyn, Kane, John L., Grover, Deepak, Woodworth, Lisa, Madore, Charlotte, Saleh, Jacqueline, Sancho, Jose, Liu, Jinyu, Li, Yi, Proto, Jonathan, Zelic, Matija, Mahan, Amy, Kothe, Michael, Scholte, Andrew A., Fitzgerald, Maria, Gisevius, Barbara, Haghikia, Aiden, Butovsky, Oleg, Ofengeim, Dimitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584629/
https://www.ncbi.nlm.nih.gov/pubmed/33097690
http://dx.doi.org/10.1038/s41419-020-03084-7