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CSF1R signaling is a regulator of pathogenesis in progressive MS
Microglia serve as the innate immune cells of the central nervous system (CNS) by providing continuous surveillance of the CNS microenvironment and initiating defense mechanisms to protect CNS tissue. Upon injury, microglia transition into an activated state altering their transcriptional profile, t...
Autores principales: | Hagan, Nellwyn, Kane, John L., Grover, Deepak, Woodworth, Lisa, Madore, Charlotte, Saleh, Jacqueline, Sancho, Jose, Liu, Jinyu, Li, Yi, Proto, Jonathan, Zelic, Matija, Mahan, Amy, Kothe, Michael, Scholte, Andrew A., Fitzgerald, Maria, Gisevius, Barbara, Haghikia, Aiden, Butovsky, Oleg, Ofengeim, Dimitry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584629/ https://www.ncbi.nlm.nih.gov/pubmed/33097690 http://dx.doi.org/10.1038/s41419-020-03084-7 |
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