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USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP
Human C-terminal binding protein (CtBP)–interacting protein (CtIP) is a central regulator to initiate DNA end resection and homologous recombination (HR). Several studies have shown that post-translational modifications control the activity or expression of CtIP. However, it remains unclear whether...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584643/ https://www.ncbi.nlm.nih.gov/pubmed/33097710 http://dx.doi.org/10.1038/s41467-020-19202-0 |