TRPV4 promotes acoustic wave-mediated BBB opening via Ca(2+)/PKC-δ pathway

INTRODUCTION: Numerous studies have shown the ability of low-energy acoustic waves such as focused ultrasound or shockwave to transiently open blood-brain barrier (BBB) and facilitate drug delivery to the brain. Preclinical and clinical evidences have well demonstrated the efficacy and safety in tre...

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Detalles Bibliográficos
Autores principales: Liao, Wei-Hao, Hsiao, Ming-Yen, Kung, Yi, Liu, Hao-Li, Béra, Jean-Christophe, Inserra, Claude, Chen, Wen-Shiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584681/
https://www.ncbi.nlm.nih.gov/pubmed/33133680
http://dx.doi.org/10.1016/j.jare.2020.06.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584681/
https://www.ncbi.nlm.nih.gov/pubmed/33133680
http://dx.doi.org/10.1016/j.jare.2020.06.012

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