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TRPV4 promotes acoustic wave-mediated BBB opening via Ca(2+)/PKC-δ pathway
INTRODUCTION: Numerous studies have shown the ability of low-energy acoustic waves such as focused ultrasound or shockwave to transiently open blood-brain barrier (BBB) and facilitate drug delivery to the brain. Preclinical and clinical evidences have well demonstrated the efficacy and safety in tre...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584681/ https://www.ncbi.nlm.nih.gov/pubmed/33133680 http://dx.doi.org/10.1016/j.jare.2020.06.012 |