MBIP (MAP3K12 binding inhibitory protein) drives NSCLC metastasis by JNK-dependent activation of MMPs

Metastasis is the cause for 90% of cancer-related mortalities. Identification of genetic drivers promoting dissemination of tumor cells may provide opportunities for novel therapeutic strategies. We previously reported an in vivo gain-of-function screen that identified ∼30 genes with a functional ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Ochieng, Joshua Kapere, Kundu, Samrat T., Bajaj, Rakhee, Rodriguez, B. Leticia, Fradette, Jared J., Gibbons, Don L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584762/
https://www.ncbi.nlm.nih.gov/pubmed/32963352
http://dx.doi.org/10.1038/s41388-020-01463-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584762/
https://www.ncbi.nlm.nih.gov/pubmed/32963352
http://dx.doi.org/10.1038/s41388-020-01463-0

Ejemplares similares