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Modeling mtDNA hypermethylation vicious circle mediating Aβ-induced endothelial damage memory in HCMEC/D3 cell

It is well accepted that accumulation of beta-amyloid (Aβ) may involve in endothelial dysfunction during the Alzheimer’s disease (AD) progression. However, cerebrovascular function cannot be improved by removing Aβ in AD animal models. The reasons for these paradoxical results still remain to be fur...

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Detalles Bibliográficos
Autores principales: Liu, HaoChen, Zhang, Hong, Zhang, Yixuan, Xu, Sheng, Zhao, Huimin, He, Hua, Liu, XiaoQuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585070/
https://www.ncbi.nlm.nih.gov/pubmed/32986015
http://dx.doi.org/10.18632/aging.103699