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Glioblastoma cell differentiation trajectory predicts the immunotherapy response and overall survival of patients

Glioblastoma (GBM) is the most common and lethal primary brain tumor. In this study, we aimed to investigate the differentiation states of GBM cells and their clinical relevance. Integrated single-cell RNA-sequencing (scRNA-seq) data and bulk RNA-seq data from GBM samples were used for analysis. Two...

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Detalles Bibliográficos
Autores principales: Wang, Zihao, Guo, Xiaopeng, Gao, Lu, Wang, Yu, Ma, Wenbin, Xing, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585071/
https://www.ncbi.nlm.nih.gov/pubmed/32957084
http://dx.doi.org/10.18632/aging.103695