D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway

Treatment of glioblastoma using radiotherapy and chemotherapy has various outcomes, key among them being cellular senescence. However, the molecular mechanisms of this process remain unclear. In the present study, we tested the ability of D-galactose (D-gal), a reducing sugar, to induce senescence i...

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Detalles Bibliográficos
Autores principales: Xu, Xingxing, Shen, Xiya, Feng, Wenjin, Yang, Danlu, Jin, Lingting, Wang, Jiaojiao, Wang, Mianxian, Ting, Zhang, Xue, Feng, Zhang, Jingjing, Meng, Chaobo, Chen, Roumeng, Zheng, Xinru, Du, Leilei, Xuan, Lina, Wang, Ying, Xie, Tian, Huang, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585072/
https://www.ncbi.nlm.nih.gov/pubmed/32991321
http://dx.doi.org/10.18632/aging.103819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585072/
https://www.ncbi.nlm.nih.gov/pubmed/32991321
http://dx.doi.org/10.18632/aging.103819

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