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GHR knockdown enhances the sensitivity of HCC cells to sorafenib

Sorafenib is approved for treatment of advanced hepatocellular carcinoma (HCC) by the Drug Administration. However, the efficacy of sorafenib has become very limited because most tumors have developed resistance to this drug. In this study, we found that sorafenib stimulated GHR expression in HCC ce...

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Detalles Bibliográficos
Autores principales: Gao, Shuang, Ni, Qianwen, Wu, Xiuli, Cao, Tieliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585089/
https://www.ncbi.nlm.nih.gov/pubmed/32970612
http://dx.doi.org/10.18632/aging.103625