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Chetomin rescues pathogenic phenotype of LRRK2 mutation in drosophila

Leucine-rich repeat kinase 2 (LRRK2) is a complex protein kinase involved in a diverse set of functions. Mutations in LRRK2 are a common cause of autosomal dominant familial Parkinson’s disease. Peroxiredoxin 2 (PRDX2) belongs to a family of anti-oxidants that protect cells from oxidative stress. Im...

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Detalles Bibliográficos
Autores principales: Chua, Ling Ling, Ho, Patrick, Toh, Joanne, Tan, Eng-King
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585092/
https://www.ncbi.nlm.nih.gov/pubmed/32990658
http://dx.doi.org/10.18632/aging.103843