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p21 can be a barrier to ferroptosis independent of p53

Traditionally, the p21 protein has been viewed as limiting cancer progression and promoting aging. In contrast, there are reports that p21 can enhance cancer survival and limit tissue damage, depending on the tissue of origin and type of stressor involved. Here, we provide evidence to support these...

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Detalles Bibliográficos
Autores principales: Venkatesh, Divya, Stockwell, Brent R., Prives, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585094/
https://www.ncbi.nlm.nih.gov/pubmed/32979260
http://dx.doi.org/10.18632/aging.103961