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Modulating redox homeostasis and cellular reprogramming through inhibited methylenetetrahydrofolate dehydrogenase 2 enzymatic activities in lung cancer

Recent reports have indicated the role of highly expressed methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) enzyme in cancers, showing poor survival; however, detailed mechanistic insight of metabolic functions of MTHFD2 have not been well-defined. Therefore, we aimed to examine the metabolic func...

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Detalles Bibliográficos
Autores principales: Chan, Chun-Hao, Wu, Chia-Yu, Dubey, Navneet Kumar, Wei, Hong-Jian, Lu, Jui-Hua, Mao, Samantha, Liang, Joy, Liang, Yu-Hsuan, Cheng, Hsin-Chung, Deng, Win-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585109/
https://www.ncbi.nlm.nih.gov/pubmed/32759461
http://dx.doi.org/10.18632/aging.103471