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Nudt21-mediated alternative polyadenylation of HMGA2 3′-UTR impairs stemness of human tendon stem cell

Tendon-derived stem cells (TSCs) play a primary role in tendon physiology, pathology, as well as tendon repair and regeneration after injury. TSCs are often exposed to mechanical loading-related cellular stresses such as oxidative stress, resulting in loss of stemness and multipotent differentiation...

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Detalles Bibliográficos
Autores principales: Sun, Yangbai, Chen, Hua, Ye, Hui, Liang, Wenqing, Lam, Kun-kuan, Cheng, Biao, Lu, Yong, Jiang, Chaoyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585117/
https://www.ncbi.nlm.nih.gov/pubmed/32979259
http://dx.doi.org/10.18632/aging.103771