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Muscle defects due to perturbed somite segmentation contribute to late adult scoliosis

Scoliosis is an abnormal bending of the body axis. Truncated vertebrae or a debilitated ability to control the musculature in the back can cause this condition, but in most cases the causative reason for scoliosis is unknown (idiopathic). Using mutants for somite clock genes with mild defects in the...

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Detalles Bibliográficos
Autores principales: Lleras-Forero, Laura, Newham, Elis, Teufel, Stefan, Kawakami, Koichi, Hartmann, Christine, Hammond, Chrissy L., Knight, Robert D., Schulte-Merker, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585121/
https://www.ncbi.nlm.nih.gov/pubmed/32979261
http://dx.doi.org/10.18632/aging.103856