Lipopolysaccharide upregulates miR-132/212 in Hirschsprung-associated enterocolitis, facilitating pyroptosis by activating NLRP3 inflammasome via targeting Sirtuin 1 (SIRT1)

Hirschsprung disease (HSCR) is a congenital disorder attributed to the failure of the neural crest derivatives migrating and/or differentiating along the hindgut. The most frequent complication in Hirschsprung disease patients is Hirschsprung-associated enterocolitis (HAEC). However, its pathogenesi...

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Detalles Bibliográficos
Autores principales: Li, Hongxing, Zhou, Lingling, Zhi, Zhengke, Lv, Xiurui, Wei, Zhonghong, Zhang, Xin, Tang, Weibing, Tong, Meiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585123/
https://www.ncbi.nlm.nih.gov/pubmed/32950974
http://dx.doi.org/10.18632/aging.103852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585123/
https://www.ncbi.nlm.nih.gov/pubmed/32950974
http://dx.doi.org/10.18632/aging.103852

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