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Regulation of E2F1 activity via PKA-mediated phosphorylations

E2F1 becomes activated during the G1 phase of the cell cycle, and posttranslational modifications modulate its activity. Activation of G-protein coupled receptors (GPCR) by many ligands induces the activation of adenylate cyclases and the production of cAMP, which activates the PKA enzyme. Activated...

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Detalles Bibliográficos
Autores principales: ERTOSUN, Mustafa Gökhan, DİLMAÇ, Sayra, HAPİL, Fatma Zehra, TANRIÖVER, Gamze, KÖKSOY, Sadi, ÖZEŞ, Osman Nidai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585165/
https://www.ncbi.nlm.nih.gov/pubmed/33110360
http://dx.doi.org/10.3906/biy-2003-9