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IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells

BACKGROUND: Epithelial-mesenchymal transition (EMT) is a key process in the onset and development of idiopathic pulmonary fibrosis (IPF) with unclear mechanisms. Our previous studies found that bleomycin and tunicamycin could induce ER stress and consequently trigger EMT accompanying with IL-32 over...

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Detalles Bibliográficos
Autores principales: Gong, Ling, Liu, Gang, Zhu, Honglan, Li, Caihong, Li, Pengmei, Liu, Changlu, Tang, Hongbo, Wu, Kaifeng, Wu, Jie, Liu, Daishun, Tang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585222/
https://www.ncbi.nlm.nih.gov/pubmed/33097029
http://dx.doi.org/10.1186/s12890-020-01319-z