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Synthesis and Identification of a Novel Peptide, Ac-SDK (Biotin) Proline, That Can Elicit Anti-Fibrosis Effects in Rats Suffering from Silicosis

BACKGROUND: N-Acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is a short peptide with an anti-silicosis effect. However, the short biological half-life and low plasma concentration of Ac-SDKP hamper discovery of specific targets in organisms and reduce the anti-silicosis effect. A novel peptide, Ac-SD...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Qian, Ye, Gao, Xuemin, Mao, Na, Geng, Yucong, Lin, Gaojie, Zhang, Guibin, Li, Han, Yang, Fang, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585281/
https://www.ncbi.nlm.nih.gov/pubmed/33116418
http://dx.doi.org/10.2147/DDDT.S262716