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Synthesis and Identification of a Novel Peptide, Ac-SDK (Biotin) Proline, That Can Elicit Anti-Fibrosis Effects in Rats Suffering from Silicosis
BACKGROUND: N-Acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is a short peptide with an anti-silicosis effect. However, the short biological half-life and low plasma concentration of Ac-SDKP hamper discovery of specific targets in organisms and reduce the anti-silicosis effect. A novel peptide, Ac-SD...
Autores principales: | Wang, Jin, Qian, Ye, Gao, Xuemin, Mao, Na, Geng, Yucong, Lin, Gaojie, Zhang, Guibin, Li, Han, Yang, Fang, Xu, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585281/ https://www.ncbi.nlm.nih.gov/pubmed/33116418 http://dx.doi.org/10.2147/DDDT.S262716 |
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