Heterozygous Loss of Yap1 in Mice Causes Progressive Cataracts

PURPOSE: Yap1 encodes an evolutionarily conserved transcriptional coactivator and functions as a down-stream effector of the Hippo signaling pathway that controls tissue size and cell growth. Yap1 contributes to lens epithelial development. However, the effect of Yap1 haplodeficiency on the lens epi...

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Detalles Bibliográficos
Autores principales: Lu, Qingxian, Zhang, Yingnan, Kasetti, Ramesh Babu, Gaddipati, Subhash, CVM, Naresh Kumar, Borchman, Douglas, Li, Qiutang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585397/
https://www.ncbi.nlm.nih.gov/pubmed/33085740
http://dx.doi.org/10.1167/iovs.61.12.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585397/
https://www.ncbi.nlm.nih.gov/pubmed/33085740
http://dx.doi.org/10.1167/iovs.61.12.21

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