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Activation-Induced Marker Expression Identifies Mycobacterium tuberculosis–Specific CD4 T Cells in a Cytokine-Independent Manner in HIV-Infected Individuals with Latent Tuberculosis

HIV infection is a significant risk factor for reactivation of latent Mycobacterium tuberculosis infection (LTBI) and progression to active tuberculosis disease, yet the mechanisms whereby HIV impairs T cell immunity to M. tuberculosis have not been fully defined. Evaluation of M. tuberculosis–speci...

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Detalles Bibliográficos
Autores principales: Barham, Morgan S., Whatney, Wendy E., Khayumbi, Jeremiah, Ongalo, Joshua, Sasser, Loren E., Campbell, Angela, Franczek, Meghan, Kabongo, Mbuyi Madeleine, Ouma, Samuel G., Hayara, Felix Odhiambo, Gandhi, Neel R., Day, Cheryl L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585460/
https://www.ncbi.nlm.nih.gov/pubmed/33008839
http://dx.doi.org/10.4049/immunohorizons.2000051