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Analysis of Xq27.3 Fragility Using the Micronucleus-Fluorescence In situ Hybridization Assay

Chromosome fragile sites tend to form gap or break in chromosomes when the cells are exposed to replication stress. Folic acid deprivation in the culture medium induces folate-sensitive rare fragile sites, such as FRAXA which is responsible for the fragile X mental retardation syndrome. Chromosome i...

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Detalles Bibliográficos
Autores principales: Özer, Leyla, Ruhi, Hatice Ilgın, Bökesoy, Işık
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585461/
https://www.ncbi.nlm.nih.gov/pubmed/33110486
http://dx.doi.org/10.4103/genint.genint_4_20