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Analysis of Xq27.3 Fragility Using the Micronucleus-Fluorescence In situ Hybridization Assay
Chromosome fragile sites tend to form gap or break in chromosomes when the cells are exposed to replication stress. Folic acid deprivation in the culture medium induces folate-sensitive rare fragile sites, such as FRAXA which is responsible for the fragile X mental retardation syndrome. Chromosome i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585461/ https://www.ncbi.nlm.nih.gov/pubmed/33110486 http://dx.doi.org/10.4103/genint.genint_4_20 |