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Aberrant effect of genistein on placenta development expressed through alteration in transforming growth factor-β1 and alkaline phosphatase across the maternal serum, the placenta and the amniotic fluid

OBJECTIVE(S): The mechanism via which genistein, the major isoflavone content of soya, adversely influenced placenta and fetal development was evaluated in pregnant laboratory rats. MATERIALS AND METHODS: There were control, 2 mg/kg and 4 mg/kg genistein groups of rats with five sub-groups based on...

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Detalles Bibliográficos
Autores principales: Awobajo, Funmileyi Olubajo, Samuel, Titilola Aderonke, Morakinyo, Ayodele Olufemi, Oyelowo, Oluwakemi Tinuolaoluwa, Onyekwele, Perpetual Uzoamaka, Medobi, Ejike Frank, Abdul, Mariam Wuraola, Aminu, Bilikisu Bukola, Oruade, Elo Onome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585541/
https://www.ncbi.nlm.nih.gov/pubmed/33149862
http://dx.doi.org/10.22038/ijbms.2020.42493.10022