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Targeting tumor cell-derived CCL2 as a strategy to overcome Bevacizumab resistance in ETV5(+) colorectal cancer

In our previous study, ETV5 mediated-angiogenesis was demonstrated to be dependent upon the PDGF-BB/PDGFR-β/Src/STAT3/VEGFA pathway in colorectal cancer (CRC). However, the ability of ETV5 to affect the efficacy of anti-angiogenic therapy in CRC requires further investigation. Gene set enrichment an...

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Detalles Bibliográficos
Autores principales: Feng, Haoran, Liu, Kun, Shen, Xiaonan, Liang, Juyong, Wang, Changgang, Qiu, Weihua, Cheng, Xi, Zhao, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585575/
https://www.ncbi.nlm.nih.gov/pubmed/33099574
http://dx.doi.org/10.1038/s41419-020-03111-7