Apigenin causes necroptosis by inducing ROS accumulation, mitochondrial dysfunction, and ATP depletion in malignant mesothelioma cells

Apigenin, a naturally occurring flavonoid, is known to exhibit significant anticancer activity. This study was designed to determine the effects of apigenin on two malignant mesothelioma cell lines, MSTO-211H and H2452, and to explore the underlying mechanism(s). Apigenin significantly inhibited cel...

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Detalles Bibliográficos
Autores principales: Lee, Yoon-Jin, Park, Kwan-Sik, Nam, Hae-Seon, Cho, Moon-Kyun, Lee, Sang-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585594/
https://www.ncbi.nlm.nih.gov/pubmed/33093271
http://dx.doi.org/10.4196/kjpp.2020.24.6.493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585594/
https://www.ncbi.nlm.nih.gov/pubmed/33093271
http://dx.doi.org/10.4196/kjpp.2020.24.6.493

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