Topical Application of S1P(2) Antagonist JTE-013 Attenuates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis in Mice

Sphingosine-1-phosphate (S1P) and its receptors have been implicated in atopic dermatitis. S1P(2) was found to function as a pro-allergic receptor, while its antagonist JTE-013 was found to suppress allergic asthma in mice. Topical application of JTE-013 has not been investigated in an in vivo model...

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Detalles Bibliográficos
Autores principales: Kang, Jisoo, Lee, Ju-Hyun, Im, Dong-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585635/
https://www.ncbi.nlm.nih.gov/pubmed/32487782
http://dx.doi.org/10.4062/biomolther.2020.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585635/
https://www.ncbi.nlm.nih.gov/pubmed/32487782
http://dx.doi.org/10.4062/biomolther.2020.036

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