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Selonsertib Inhibits Liver Fibrosis via Downregulation of ASK1/MAPK Pathway of Hepatic Stellate Cells

Liver fibrosis constitutes a significant health problem worldwide due to its rapidly increasing prevalence and the absence of specific and effective treatments. Growing evidence suggests that apoptosis-signal regulating kinase 1 (ASK1) is activated in oxidative stress, which causes hepatic inflammat...

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Detalles Bibliográficos
Autores principales: Yoon, Young-Chan, Fang, Zhenghuan, Lee, Ji Eun, Park, Jung Hee, Ryu, Ji-Kan, Jung, Kyung Hee, Hong, Soon-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585640/
https://www.ncbi.nlm.nih.gov/pubmed/32451370
http://dx.doi.org/10.4062/biomolther.2020.016