Mogroside IIIE Alleviates High Glucose-Induced Inflammation, Oxidative Stress and Apoptosis of Podocytes by the Activation of AMPK/SIRT1 Signaling Pathway

BACKGROUND: Diabetic nephropathy (DN) is the leading cause of impaired renal function. The purpose of this study was to investigate the effects of Mogroside IIIE (MG IIIE), a cucurbitane-type compound isolated from Siraitia grosvenorii, in high glucose (HG)-induced podocytes and the possible mechani...

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Detalles Bibliográficos
Autores principales: Xue, Wei, Mao, Juhua, Chen, Qingjie, Ling, Weide, Sun, Yuqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585782/
https://www.ncbi.nlm.nih.gov/pubmed/33116729
http://dx.doi.org/10.2147/DMSO.S276184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585782/
https://www.ncbi.nlm.nih.gov/pubmed/33116729
http://dx.doi.org/10.2147/DMSO.S276184

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