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Mogroside IIIE Alleviates High Glucose-Induced Inflammation, Oxidative Stress and Apoptosis of Podocytes by the Activation of AMPK/SIRT1 Signaling Pathway

BACKGROUND: Diabetic nephropathy (DN) is the leading cause of impaired renal function. The purpose of this study was to investigate the effects of Mogroside IIIE (MG IIIE), a cucurbitane-type compound isolated from Siraitia grosvenorii, in high glucose (HG)-induced podocytes and the possible mechani...

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Detalles Bibliográficos
Autores principales:	Xue, Wei, Mao, Juhua, Chen, Qingjie, Ling, Weide, Sun, Yuqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585782/ https://www.ncbi.nlm.nih.gov/pubmed/33116729 http://dx.doi.org/10.2147/DMSO.S276184

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