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Inflammation Mediated Hepcidin-Ferroportin Pathway and Its Therapeutic Window in Breast Cancer

Experimental and clinical data strongly support that iron is an essential element which plays a big role in cancer biology. Thus, hepcidin (Hp) and ferroportin (Fpn) are molecules that regulate and maintain the metabolism of iron. A peptide hormone hepcidin limits recycled and stored iron fluxes in...

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Detalles Bibliográficos
Autores principales: Shibabaw, Tewodros, Teferi, Banchamlak, Molla, Meseret Derbew, Ayelign, Birhanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585830/
https://www.ncbi.nlm.nih.gov/pubmed/33116818
http://dx.doi.org/10.2147/BCTT.S276404