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SERCA Overexpression Improves Mitochondrial Quality Control and Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury

Despite significant advances in the treatment of myocardial ischemia-reperfusion (I/R) injury, coronary circulation is a so far neglected target of cardioprotection. In this study, we investigated the molecular mechanisms underlying I/R injury to cardiac microcirculation. Using gene delivery, we ana...

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Detalles Bibliográficos
Autores principales: Tan, Ying, Mui, David, Toan, Sam, Zhu, Pingjun, Li, Ruibing, Zhou, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585837/
https://www.ncbi.nlm.nih.gov/pubmed/33230467
http://dx.doi.org/10.1016/j.omtn.2020.09.013