Endothelial prostaglandin D(2) opposes angiotensin II contractions in mouse isolated perfused intracerebral microarterioles

HYPOTHESIS: A lack of contraction of cerebral microarterioles to Ang II (“resilience”) depends on cyclooxygenase (COX) and lipocalin type prostaglandin D sythase L-PGDS producing PGD(2) that activates prostaglandin D type 1 receptors (DP1Rs) and nitric oxide synthase (NOS). MATERIALS & METHODS:...

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Detalles Bibliográficos
Autores principales: Li, L, Lai, EY, Cao, X, Welch, WJ, Wilcox, CS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585895/
https://www.ncbi.nlm.nih.gov/pubmed/33094663
http://dx.doi.org/10.1177/1470320320966177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585895/
https://www.ncbi.nlm.nih.gov/pubmed/33094663
http://dx.doi.org/10.1177/1470320320966177

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