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The SRSF3-MBNL1-Acin1 circuit constitutes an emerging axis to lessen DNA fragmentation in colorectal cancer via an alternative splicing mechanism

Altered alternative splicing (AS) events are considered pervasive causes that result in the development of carcinogenesis. Herein, we identified reprogrammed expression and splicing profiles of Muscle blind-like protein 1 (MBNL1) transcripts in tumorous tissues compared to those of adjacent normal t...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Su, Liu, Chao-Wei, Lin, Ying-Chin, Tsai, Chia-Ying, Yang, Ching-Hui, Lin, Jung-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586066/
https://www.ncbi.nlm.nih.gov/pubmed/33142236
http://dx.doi.org/10.1016/j.neo.2020.10.002