Lung Carcinoma Cells Secrete Exosomal MALAT1 to Inhibit Dendritic Cell Phagocytosis, Inflammatory Response, Costimulatory Molecule Expression and Promote Dendritic Cell Autophagy via AKT/mTOR Pathway

OBJECTIVE: To investigate the potential mechanism underlying the effect of lung carcinoma cell-derived exosomes on dendritic cell function. MATERIALS AND METHODS: C57BL/6 (B6) mice were randomly divided into five groups: control, dendritic cell (DC), DC-NC, DC-siMALAT1, and siMALAT1. Tumor cell prol...

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Detalles Bibliográficos
Autores principales: Liu, Yanyan, Yin, Zhucheng, Lu, Ping, Ma, Yifei, Luo, Bo, Xiang, Lanxin, Zhang, Wangli, He, Yu, Liang, Xinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586126/
https://www.ncbi.nlm.nih.gov/pubmed/33116646
http://dx.doi.org/10.2147/OTT.S256669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586126/
https://www.ncbi.nlm.nih.gov/pubmed/33116646
http://dx.doi.org/10.2147/OTT.S256669

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