TERT promoter mutation associated with multifocal phenotype and poor prognosis in patients with IDH wild-type glioblastoma

BACKGROUND: Although mutations in the promoter region of the telomerase reverse transcriptase (TERTp) gene are the most common alterations in glioblastoma (GBM), their clinical significance remains unclear. Therefore, we investigated the impact of TERTp status on patient outcome and clinicopathologi...

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Detalles Bibliográficos
Autores principales: Kikuchi, Zensho, Shibahara, Ichiyo, Yamaki, Tetsu, Yoshioka, Ema, Shofuda, Tomoko, Ohe, Rintaro, Matsuda, Ken-ichiro, Saito, Ryuta, Kanamori, Masayuki, Kanemura, Yonehiro, Kumabe, Toshihiro, Tominaga, Teiji, Sonoda, Yukihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586143/
https://www.ncbi.nlm.nih.gov/pubmed/33134923
http://dx.doi.org/10.1093/noajnl/vdaa114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586143/
https://www.ncbi.nlm.nih.gov/pubmed/33134923
http://dx.doi.org/10.1093/noajnl/vdaa114

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